translation mechanisms and control buyer’s guide for 2022
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1. Translation Mechanisms and Control
Description
Translation converts the genetic code in messenger RNA molecules copied from DNA into a specific sequence of amino acids in a protein. It occurs on ribosomes in the cell cytoplasm and is one of the most fundamental biological processes. This volume examines the detailed molecular machinery responsible for translation and the regulatory mechanisms that make the process a critical control point for the cell.Topics covered in this essential volume include:
- History of Protein Synthesis and Translational Control
- Protein Synthesis Initiation in Eukaryotic Cells
- Translation in Prokaryotes
- New Insights into Ribosome Structure and Function
- Translational Control in Virus-Infected Cells
- Translating Therapeutics
2. Mechanisms of Protein Synthesis: Structure-Function Relations, Control Mechanisms, and Evolutionary Aspects (Proceedings in Life Sciences)
Feature
Used Book in Good ConditionDescription
This volume contains the papers presented at the international symposium on "Molecular Mechanisms in Protein Synthesis" held on September 26-27, 1983 at the Beyaz Kok in Emirgan, Bosphorus, Istanbul. The symposium aimed to create a medium for information exchange and discussions regarding the current developments in the area of protein syn thesis. To ensure an informal yet scientifically stimulating and productive atmosphere providing opportunity for relaxed and speculative discussions, the number of presentations was limited to twenty and that of attendants to about sixty. The emphasis in the symposium was laid on structure-function relations in the prokaryotic protein synthesizing systems and on the control mechanisms of eukaryotic protein synthesis, in particular, during chain initia tion. Other issues like evolutionary aspects of protein synthesis, translational components genes and proofreading were covered as well. The manuscripts represent the extended accounts of the oral presenta tions, and it has been aimed with the concluding remarks at the end of the volume to give a summarizing view of the presentations and the discussions.3. Transcription Factors: Methods and Protocols (Methods in Molecular Biology)
Description
In the last few years, significant breakthroughs in transcription research expanded our appreciation for the complexity of molecular controls on gene expression in mammalian cells. In Transcription Factors: Methods and Protocols, experts in the field describe state-of-the-art approaches that investigators can use to probe critical mechanisms underlying transcription factor nuclear-cytoplasmic trafficking as well as to assess the functional impact of post-translational modifications on transcription factor function. The chapters are written by prominent scientists, many of whom developed these methods, and highlight protocols that focus on specific transcription factor family members with particular relevance to human disease. Composed in the highly successful Methods in Molecular Biology series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls.
Comprehensive and current, Transcription Factors: Methods and Protocols compiles the latest techniques for elucidating controls on transcription factor intracellular localization and activity, and consequently is unlike any other methods-based text on transcriptional regulation today.
4. LTP mechanisms in the dentate gyrus in vivo: BDNF signaling, translation control, and gene function
Description
This book illustrates some of the various molecular mechanisms underlying synaptic plasticity in a subfield of the rat hippocampus called dentate gyrus (DG). Long-term potentiation (LTP) is a well- known model for studying strengthening of synaptic plasticity. In this study, LTP was induced in the DG by intrahippocampal infusion of brain-derived neurotrophic factor (BDNF-LTP). Alternatively, LTP was induced at medial perforant path-granule cell synapses by high frequency stimulation (HFS-LTP). The aim of the study was investigation of transcriptional and translational changes of activity-regulated cytoskeleton-associated protein (Arc/Arg3.1) as well as changes in activation of the translation factors eIF4E (eukaryotic initiation factor 4E) and eEF2 (eukaryotic elongation factor-2) during LTP. We have demonstrated rapid activation of both translation factors and upregulation of Arc protein during BDNF-LTP. Additionally, an approach based on intrahippocampal infusion of Arc antisense oligodeoxynucleotides showed the importance of sustained Arc translation for the maintenance of both BDNF-LTP and HFS-LTP during a restricted time window.5. Accuracy in Molecular Processes: Its Control and Relevance to Living System
Feature
Used Book in Good ConditionDescription
Molecular biology proceeds at unremitting pace to unfold new secrets of the living world. Biology, long regarded as an inexact companion to physics and chemistry, has undergone transformation. Now, chemical and physical principles are tools in understanding highly complex biomolecular processes, whose origin lies in a history of chance, constraint and natural selection. The accuracy of these processes, often remarkably high, is crucial to their self perpetuation, both individually and collectively, as ingredients of the organism as a whole. In this book are presented thirteen chapters which deal with various facets of the accuracy problem. Subjects covered include: the specificity of enzymes; the fidelity of synthesis of proteins; the replication and repair of DNA: general schemes for the enhancement of biological accuracy; selection for an optimal balance between the costs and benefits of accuracy; and the possible relevance of molecular mistakes to the process of ageing. The viewpoints are distinct, yet complementary, and the book as a whole offers to researchers and students the first comprehensive account of this growing field.6. Post-Transcriptional Gene Regulation (Methods in Molecular Biology)
Description
This volume strives to present current technical approaches to most aspects of post-transcriptional control and provide the reader with a useful and versatile laboratory bench resource. With chapters split into sections covering bioinformatics, fundamental aspects of the study of RNA biology, and techniques for specific aspects of RNA biology, the expert authors have filled the book with invaluable tricks of the trade, perfected in their laboratories.
7. LEM7 Smart Watch Android 7.0 Smartwatch LTE 4G Smart Watch Phone Heart Rate 1GB + 16GB Memory Camera Translation Tool, Black
Feature
Function:Passometer,Heart Rate Tracker,Fitness Tracker,Message Reminder,Calendar,Dial Call,Push Message,Alarm Clock,Remote Control,Month,Answer Call,Week,Call ReminderLanguage:Portuguese,Spanish,English,Hebrew,German,Arabic,Japanese,Indonesian,Polish,Korean,Russian,Italian,French,Turkish
Case Material:Alloy
GPS:Yes
APP Download Available:Yes
Description
Battery Capacity:>450mAh
Screen Size:1.39inch
Screen Shape:Round
Band Detachable:No
Application Age Group:Adult
Band Material:Silica Gel
System:Android OS
Multiple Dials:Yes
CPU Manufacturer:Mediatek
Resolution:400*400px
Rear Camera:2MP
Compatibility:All Compatible
CPU Model:MT6737M
Battery Detachable:No
Type:On Wrist
Network Mode:4G
Waterproof Grade:Life Waterproof
ROM:16GB
SIM Card Available:Yes
RAM:1GB
Mechanism:No
Unit Type: piece
Package Weight: 0.28kg (0.62lb.)
Package Size: 10cm x 10cm x 10cm (3.94in x 3.94in x 3.94in)
8. OMAX 40X-2000X Trinocular Biological Compound Microscope with Replaceable LED Light
Feature
Total magnification: 40X-80X-100X-200X-400X-800X-1000X-2000X; Eyepieces: widefield WF10X/18 and WF20X; Objectives: achromatic DIN 4X, 10X, 40X (S), 100X (S, Oil); Viewing head: 45 degrees inclined 360 degrees swiveling trinocular; Interpupillary distance: sliding adjustable 2-3/16inch ~ 2-15/16inch (55mm ~ 75mm); Diopter: adjustable on both eyepiece tubesNosepiece: revolving quadruple; Stage: mechanical stain-resistant double layer, size: 5-1/2inch x 5-1/2inch (140mm x 140mm), translation range: 3inch x 2inch (75mm x 50mm); Photo tube adjustment range: 5/8inch (15mm); Focus: coaxial coarse and fine focus knobs on both sides, rack and pinion adjustment, with tension control; Focusing knob can be locked for observation and transportation
Condenser and diaphragm: Abbe NA1.25 rack and pinion adjustment condenser with iris aperture diaphragm; Black palm rest on the base; Illumination: transmitted (lower), replaceable 3W LED light, variable intensity
Metal mechanical components; Condenser and diaphragm: NA1.25 Abbe condenser with iris diaphragm; Power supply: 100V~240V 50/60Hz worldwide range (US and Canada power plug)
5-year warranty against manufacturing defects
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